Want to improve your memory as Eidetic memory or photographic memory? Here we discuss 6 Best Uridine Monophosphate supplement for Enhance Memory and Anxiety-depression Treatment. Uridine is one of the best nootropics to increase the ability to learn quickly and to learn capacity.

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Best Uridine Monophosphate Supplement

Uridine Monophosphate increases synaptic plasticity to neurons to form new connections with easy process. It synchronizes several neural connections to the central nervous system and functions as mood changers.

As a senior, you can preserve and enhance your grey matter as you age. By taking the uridine supplement, there are lots you can do to improve your memory, relieve from anxiety, and mental performance.

The 5 Best Uridine Monophosphate Supplement

Wouldn’t it be wonderful to get Memory Boosters, sharpen your mind, boost your mental performance, remove anxiety or preserve your memory as you age?

1. Alpha GPC Choline Supplement – Nootropic for Brain Support, Focus, Memory, Motivation, and Energy

Are you experiencing any of the following? Memory loss or reaction time issues, Low mood or increased anxiety, Brain fog, Trouble sleeping? Then Alpha GPC Choline Supplement is the best solution for you. According to the American College of Nutrition, up to 90% of Americans are deficient in choline. Alpha GPC uridine monophosphate is a highly bioavailable form of Choline. It helps support cognitive function, mood, and motivation. You can experience brain fog, headaches, severe heartburn, and stomach pain if you don’t care about dosage.

  • Alpha GPC promote CHOLINE LEVELS as it is a highly bioavailable form of Choline which helps support healthy Choline levels
  • it crosses the blood brain barrier more easily than many other choline supplements and is effective at supporting choline levels.
  • Nootropics supplement to support memory, focus, and acetylcholine levels
  • manufactured right here in the USA

2. Uridine Monophosphate – Choline Enhancer, Beginner Nootropic 300mg

If you want far more confident in social situations and effectiveness in boosting cognition and motivation, promoting dopamine up-regulation then it is a perfect supplement to experiment with.

  • Uridine increases synthesis of brain phosphatidylcholine
  • It assists in the formation of synaptic connections in the brain
  • It may increase cholinergic brain function, and upregulate dopamine receptors.
  •  It is one of the nootropics in the mr happy stack along with Alpha GPC Choline.

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4. CDP Choline (Citicoline) Supplement, Pharmaceutical Grade, Made in USA

5. Alpha GPC and Uridine Stack – Mr Happy Stack – Uridine Monophosphate

Alpha GPC uridine monophosphate contains a significant amount of Bioavailable Choline nutrient which is formulated to develop your focus and mental clarity, cognition health, and repair dopamine receptor.  

And uridine stake is formulated to promote your memorization and learning capability and overall mental performance.

  • This Alpha GPC can naturally enhance your brain including cognition, brain activity, and overall mental performance.
  • Besides, it contains an enormous amount of choline nutrient which is necessary for your health and body function. 
  •  Uridine supplies CDP-choline to your central nervous system which develops your brain health including memory, attention span, multi-tasking and problem-solving capability. It also generates your dopamine production and improves your mode.  
  • Uridine promotes your synapse growth and neuroplasticity which are important for your short-term and long-term memory development.

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What is Uridine- Uridine Monophosphate?

  • Uridine Monophosphate is one of the five standard nucleosides which make adenosine, thymidine, cytidine and guanosine. Source
  • Uridine is a natural body substance ( nucleic acid) that is produced in the liver. It is a substrate that is used for the synthesis of phospholipids in the brain. 

Uridine has nucleic acid, which is combined with a pyrimidine base( a chemical compound derived from phosphoric acid and the nucleoside uridine). This supplement is one of the four essential components of RNA (Ribonucleic Acid). As another difference, RNA uses a ribonucleotide called uridine (the nucleotide uracil bound to a ribose sugar) to translate the DNA code. uridine structure [1, 2].

Uridine structure: Acidity (pKa)‎: ‎1.0, 6.4, 9.5Solubility in water‎: ‎good, also in methanolChemical formula‎: ‎C9H13N2O9PCAS Number‎: ‎58-97-9

  • It regulates our pyrimidine metabolism process. It champions sound sleep throughout the night.
  • Uridine plays a key role in phospholipid synthesis, critical for cell membrane integrity (uridine cycling)
  • Supports synaptogenesis and neuroplasticity through increasing cerebral phosphatidylcholine levels
  • Involved in long term potentiation which mediates memory and learning
  • Synergistic with choline donors, DHA, and other phospholipids
  • uridine 5 monophosphate : Uridine monophosphate (UMP), also known as 5′-uridylic acid (conjugate base uridylate), is a nucleotide that is used as a monomer in RNA. Uridine 5‘-monophosphate is a pyrimidine ribonucleoside 5‘-monophosphate having uracil as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite.  Source

Uridine is one of the four main building blocks of RNA aside from radenosine, cytidine, and guanine

Uridine Monophosphate Powder

Uridine is one of the core parts of RNA, and it contributes to repair your DNA and your cell growth. You cannot take uridine alone as a supplement. For effective results, you must take uridine in the form of either Uridine Monophosphate (UMP) or Triacetyluridine (TAU). Both of these forms are available online in the form of powder and capsule.

Uridine is taken for relieving depression, anxiety, nerve pain, and insomnia. Also, Uridine improves heart condition, forms new synapses in the brain, grows learning and memorizing capability, and develops other physical and cognitive health.

Uridine Monophosphate for memory improvement

Various studies experimented on rats, revealed that uridine produces new neurons as well as forms new synapses in the brain.

Massachusetts Institute of Technology conducted a research on 259 patients with Alzheimer’s disease. Patients who were given Souvenaid containing uridine performed better in verbal memory tasks. The same research also revealed that uridine can form new synaptic in the human brain.

Uridine Monophosphate for Anxiety and Depression

Many uridine consumers commented that their general motivation has increased, and they have developed a sense of potentiality. After taking uridine monophosphate you will have a feeling of unimpeded. Also, your current psychiatric or emotional issues will disappear within a week, and you will start feeling just awesome.  In short, it will enhance your overall cognition functionality and your attention span too.

Uridine and Sleep Disorder

People who are experiencing sleep disorder or insomnia, can take uridine monophosphate as a solution.  Uridine monophosphate is considered as a potential sleep aid for adults. Source and article link- Honda KKomoda YNishida SNagasaki HHigashi AUchizono KInoué S.

Breast milk contains uridine, but a research conducted on 30 infants who were having sleep disorders. These infants were given uridine before bedtime, and they didn’t show any sign of sleep disorder throughout the night.

Uridine Dopamine Receptors

Does uridine increase dopamine?

Uridine Monophosphate raises neural (brain) Uridine levels. Uridine Monophosphate is a dopamine receptor modulator A balanced amount of dopamine is a requisite to optimize your cognition functionality including maintaining motivation, learning ability, and attention span.

Uridine dopamine deficiency can cause hyperactive disorder, attention deficit, continuous anxiety, and unipolar depression. Contrarily, if the dopamine level exceeds the normal level, it can cause bipolar disorder or extreme mood swings. Uridine-5′-monophosphate supplementation increases potassium-evoked dopamine release. Source

You may find some common pharmaceutical drugs available on the market which treats dopamine imbalance. You may find these drugs beneficial but for the short term, and these drugs may trigger side-effects including high blood pressure or any physiological overload.  These drugs can merely cover your symptoms for a short time, but they cannot correct your dopamine imbalance problem for a long time or permanently.

A recent study revealed that nootropic stack with uridine can correct one’s dopamine imbalance for a long time.

Uridine Dosage

· It’s also potentially dangerous in too high amounts, so caution is always wise.

Correct uridine dose may improve brain function, relieve depression and nerve pain, and protect the heart.

 Make sure to distribute the prescribed quantity throughout the day evenly. It will help ensure that one has the correct amount of uridine dosage in the body. Correct uridine dose helps conserve overall mental health and remove anxiety. As a dietary supplement, take 150-250mg of Uridine dose once daily.

Uridine monophosphate dosage for nootropic benefit is 150 – 250 mg per day twice per day. 

Uridine Benefits: 6 Uridine Monophosphate benefits

What does uridine monophosphate do? Uridine monophosphate plays a key role in many different neuroregulatory processes. It is believed to support short and long term memory, learning, attention, and executive function.

Uridine Monophosphate Benefits-uridine Benefits
uridine monophosphate benefits
Uridine Monophosphate Benefits-uridine Benefits

Top 6 uridine monophosphate benefits

  • 1. Cognitive enhancer, creativity, or motivation, relieve nerve pain. Apart from relieving nerve pain uridine prevents dementia
  • 2. Uridine supplement for memory to enhance memory
  • 3. Helps in bipolar disorder, mitochondrion working, and depression
  • 4. Alternatively, a combination of uridine monophosphate, vitamin B12 and folic acid can be used as a pain killer for patients with carpal tunnel syndrome.  Cure condenses ache and tenderness
  • 5. Uridine supplements reduce daydreaming, amnesia (uridine monophosphate anxiety), and increase concentration, positive mood, and focus. 
  • 6. Increase gray matter in the brain and improve spatial working memory.

Read more: uridine hair growth

Triacetyluridine (TAU) 

Uridine triacetate, formerly known as vistonuridine, is a uridine supplement that is occasionally used as a nootropic supplement. Triacetyluridine (TAU)  is an orally active tri-acetylated prodrug of uridine use to decreases depressive symptoms and increases brain pH in bipolar patients.  Triacetyluridine and uridine tend to work well with lipids and phospate groups. Triacetyluridine tends to behave synergistically with choline and fish oil to enhance mood

Triacetyluridine dosage

As a dietary supplement, take 25mg of Triacetyluridine once daily.

The nootropic benefits of Uridine Monophosphate

Discover why we use Uridine Monophosphate as a nootropic, recommended dosage, side effects and clinical research.

Uridine Side Effects – uridine dangers

Compare to other medicines/solutions taken for dopamine imbalance correction, nootropic drugs with uridine has fewer side effects. However, a few uridine consumers mentioned about experiencing emotional blunting upon taking too much uridine monophosphate doses.

1. Uridine may slow down bone development. After 25 bone stops growth. So after 30, it has no impact on bone

2. It may result to heart illness. 

3. uridine in pregnancy – So is there any complicacy of using uridine (uridine in pregnancy). It is still on research.

4. Other common effects include queasiness and diarrhea. Also, it can cause itchiness and breakouts on the skin. Taking too much uradine monophosphate sometimes causes vomiting too. So, it is compulsory to make sure that you take a prescribed dosage.

Uridine doesn’t have a lot of side effects. Uridine dangers happen if you take more dosage.

Uridine monophosphate mechanism

Uridine probably acts by generating both CTP, which can be limiting in phosphatide synthesis, and UTP, which activates P2Y receptors coupled to neurite outgrowth and protein synthesis. All three compounds also act by enhancing the substrate-saturation of phosphatide-synthesizing enzymes. – source:ncbi

uridine triacetate was discontinued for adverse reactions in 2 patients; serious adverse reactions  Source

Alpha Gpc Examine

Alpha-glycerophosphocholine (AlphaGPC or αGPC) is a cholinergic compound that is used for its cognitive-promoting properties. Alpha gpc dopamine enhances dopamine and improve your mood and motivation to  work further. Read user ratings and ALPHAGPC reviews on WebMD. 

Uridine triphosphate

Uridine triphosphate, also known as 5′-UTP or H4UTP,  is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1′ carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5′ position. Source

uridine triphosphate sigma

uridine triphosphate test


What is Uridine good for?

Uridine is one of the building blocks of RNA. And its function is to store memories. By taking a uridine supplement helps to increase the levels of RNA in your brain.

It can help memory enhancement, mental performance, remove anxiety

What is uridine monophosphate used for?

It escalates neuroplasticity as well as synaptogenesis by raising erudite phosphatidylcholine concentration to help create dendrite membranes. Uradine monophosphate powder offers potential benefits to your physical, mental and cognitive health.

Uridine monophosphate signals the creation of neurotransmitter synapses and promoting the repair of DNA and growth of cells. 

What foods contain Uridine?

  1. Tomatoes (0.5 to 1.0 g uridine per kilogram dry weight)
  2. Brewer’s yeast (1.7% uridine by dry weight)
  3. Broccoli Green fresh
  4. Offal (liver, pancreas, etc.)
  5. Walnuts.
  6. Sugarcane extract.

Does uridine increase dopamine?

Yes, It is. Uridine works with CDP Choline stimulate the development of new dopamine receptors in the brain by activating D1 and D2 receptor signaling.

Some term: uridine nutritional yeast, uridine cycling, uridine monophosphate anxiety

Does tyrosine increase dopamine?

One amino acid called tyrosine plays a critical role in the production of dopamine. Researchers found that increasing the amount of tyrosine and phenylalanine in the diet can increase dopamine levels in the brain and activate nerve.

DISCLAIMER: Always consult with a qualified health physician before taking any new dietary supplement. 

How long does uridine take to work

Uridine monophosphate dosage for nootropic benefit is 150 – 250 mg per day twice per day.  And after one week you will feel the difference.

 Uridine monophosphate plays a key role in phospholipid synthesis, critical for cell membrane integrity

docosahexaenoic acid:Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina.

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The research was taken from Dr. Prof. Raoul Orvieto

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